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CD4 抗体 (AA 245-392)

This anti-CD4 antibody is a 小鼠 单克隆 antibody detecting CD4 in ELISA 和 Coat. Suitable for 人.
产品编号 ABIN6941041
发货至: 中国

Quick Overview for CD4 抗体 (AA 245-392) (ABIN6941041)

抗原

See all CD4 抗体
CD4

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD4 antibody is un-conjugated

应用范围

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ELISA, Coating (Coat)

克隆位点

CD4-1604
  • 抗原表位

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    AA 245-392

    特异性

    Recognizes a protein of 55 kDa, identified as CD4. It is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. The majority of peripheral T-cell lymphomas are derived from the T-helper/regulatory cell subset so that most mature T-cell neoplasms are CD4+/CD8-. Anti-CD4 is used in the immunohistochemical staining of lymphoproliferative disorders to evaluate tumors with CD4 aberrant expression.

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant human CD4 protein fragment (around aa 245-392) (exact sequence is proprietary)

    亚型

    IgG2b kappa
  • 应用备注

    Positive Control: Human peripheral blood mononuclear cells (PBMCs), CCRF-CEM or HL-60. Lymph node or tonsil.

    Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    CD4

    别名

    CD4

    分子量

    55kDa

    基因ID

    920

    UniProt

    P01730

    途径

    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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